Tg(tetO-Ppp3ca*)CN279Kndl
Transgene Detail

Summary

• Symbol: Tg(tetO-Ppp3ca*)CN279Kndl
• Name: transgene insertion CN279, Eric R Kandel
• MGI ID: MGI:3809247
• Synonyms: deltaCaM-AI
• Transgene: Tg(tetO-Ppp3ca*)CN279Kndl Location: unknown
• Alliance: Tg(tetO-Ppp3ca*)CN279Kndl page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Constitutively active, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A cDNA encoding a truncated and active form of the murine calcineurin catalytic subunit, CaM-AI, which lacks the autoinhibitory domain and a portion of the calmodulin-binding domain of calcineurin, was placed under the control of the tetO promoter. (J:45600)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:45600 Mansuy IM, et al., Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell. 1998 Jan 9;92(1):39-49
• All: 8 reference(s)