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Krt16tm1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Krt16tm1(KOMP)Vlcg
Name: keratin 16; targeted mutation 1, Velocigene
MGI ID: MGI:3808273
Synonyms: Krt16tm1Vlcg
Gene: Krt16  Location: Chr11:100246091-100248902 bp, - strand  Genetic Position: Chr11, 63.44 cM
Mutation
origin
Mutant Cell Lines:  10501A-A5, 10501A-E2, 10501A-F2, 10501B-H1
Germline Transmission:  Earliest citation of germline transmission: J:184621
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 2674bp between positions 100107528-100110201 of Chromosome 11 (Genome Build37). (J:136110)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Krt16 Mutation:  11 strains or lines available
Notes
Mutant cell lines 10501A-E2 and 10501B-H1 have been used to generate chimeras but failed to establish germline transmission.
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory