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Klf5tm1Jaw
Targeted Allele Detail
Nomenclature
Symbol: Klf5tm1Jaw
Name: Kruppel-like factor 5; targeted mutation 1, Jeffrey A Whitsett
MGI ID: MGI:3806635
Synonyms: Klf5loxP
Gene: Klf5  Location: Chr14:99298691-99313412 bp, + strand  Genetic Position: Chr14, 49.43 cM, cytoband E2.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138576
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. (J:138576)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 17 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Klf5 Mutation:  11 strains or lines available
References
Original:  J:138576 Wan H, et al., Kruppel-like factor 5 is required for perinatal lung morphogenesis and function. Development. 2008 Aug;135(15):2563-72
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory