Ndst3^tm1.1Grob
Targeted Allele Detail

Summary

• Symbol: Ndst3^tm1.1Grob
• Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3; targeted mutation 1.1, Kay Grobe
• MGI ID: MGI:3806156
• Gene: Ndst3 Location: Chr3:123319815-123484502 bp, - strand Genetic Position: Chr3, 54.58 cM, cytoband G3
• Alliance: Ndst3^tm1.1Grob page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138557
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Germ line, cre-mediated recombination was used to remove exon 2 cassette. (J:138557)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ndst3 Mutation: 66 strains or lines available

References

• Original: J:138557 Pallerla SR, et al., Altered heparan sulfate structure in mice with deleted NDST3 gene function. J Biol Chem. 2008 Jun 13;283(24):16885-94
• All: 2 reference(s)