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Ezh2tm1.1Sho
Targeted Allele Detail
Nomenclature
Symbol: Ezh2tm1.1Sho
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit; targeted mutation 1.1, Stuart Orkin
MGI ID: MGI:3805309
Synonyms: Ezh2-
Gene: Ezh2  Location: Chr6:47530139-47595341 bp, - strand  Genetic Position: Chr6, 22.92 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134477
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 16 and 17 containing part of the catalytic SET domain flanked by a set of loxP in Ezh2tm1Sho were deleted. (J:134477)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ezh2 Mutation:  38 strains or lines available
References
Original:  J:134477 Puschendorf M, et al., PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nat Genet. 2008 Apr;40(4):411-20
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory