About   Help   FAQ
Targeted Allele Detail
Symbol: Ezh2tm1.1Sho
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit; targeted mutation 1.1, Stuart Orkin
MGI ID: MGI:3805309
Synonyms: Ezh2-
Gene: Ezh2  Location: Chr6:47530274-47595270 bp, - strand  Genetic Position: Chr6, 22.92 cM, cytoband B
Germline Transmission:  Earliest citation of germline transmission: J:134477
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 16 and 17 containing part of the catalytic SET domain flanked by a set of loxP in Ezh2tm1Sho were deleted. (J:134477)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ezh2 Mutation:  53 strains or lines available
Original:  J:134477 Puschendorf M, et al., PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nat Genet. 2008 Apr;40(4):411-20
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory