Pth2r^tm1Mws
Targeted Allele Detail

Summary

• Symbol: Pth2r^tm1Mws
• Name: parathyroid hormone 2 receptor; targeted mutation 1, Mark W Sleeman
• MGI ID: MGI:3804965
• Synonyms: PTH2R-beta-gal, PTH2R-lacZ
• Gene: Pth2r Location: Chr1:65321215-65428403 bp, + strand Genetic Position: Chr1, 33.05 cM, cytoband C3
• Alliance: Pth2r^tm1Mws page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132842
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (129S/SvEv x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first protein coding exon was replaced by the bacterial lacZ coding sequence. Beta-galactosidase is detectable in Pth2r-expressing neurons. (J:132842)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pth2r Mutation: 32 strains or lines available

References

• Original: J:132842 Faber CA, et al., Distribution of tuberoinfundibular peptide of 39 residues and its receptor, parathyroid hormone 2 receptor, in the mouse brain. J Comp Neurol. 2007 Jun 1;502(4):563-83
• All: 8 reference(s)