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Tg(MSLN-TAg)270iLake
Transgene Detail
Summary
Symbol: Tg(MSLN-TAg)270iLake
Name: transgene insertion 270i, Richard A Lake
MGI ID: MGI:3804827
Synonyms: MexTAg
Transgene: Tg(MSLN-TAg)270iLake  Location: unknown  
Alliance: Tg(MSLN-TAg)270iLake page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA 1,850 bp fragment of the human mesothelin promoter drives expression of the SV40 large T antigen. This transgene is expressed in mesothelial cells. Transgenic line 270i carries 15 copies of the transgene. In addition, lines 299h, 304i and 266s were also created. (J:116125)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:116125 Robinson C, et al., A novel SV40 TAg transgenic model of asbestos-induced mesothelioma: malignant transformation is dose dependent. Cancer Res. 2006 Nov 15;66(22):10786-94
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/07/2025
MGI 6.24
The Jackson Laboratory