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Tnkstm1.1Yjc
Targeted Allele Detail
Nomenclature
Symbol: Tnkstm1.1Yjc
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; targeted mutation 1.1, Y Jeffrey Chiang
MGI ID: MGI:3804704
Synonyms: TANK1-
Gene: Tnks  Location: Chr8:34829179-34965690 bp, - strand  Genetic Position: Chr8, 21.16 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137985
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was removed by germ line, cre-mediated recombination. The absence of protein expression was confirmed by western blot analysis on testis, kidney and spleen extracts. (J:137985)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnks Mutation:  19 strains or lines available
References
Original:  J:137985 Chiang YJ, et al., Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development. PLoS One. 2008;3(7):e2639
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory