Gnai1^tm1Lbi
Targeted Allele Detail

Summary

• Symbol: Gnai1^tm1Lbi
• Name: G protein subunit alpha i1; targeted mutation 1, Lutz Birnbaumer
• MGI ID: MGI:3803636
• Synonyms: Gnao1.1^tm1LBi
• Gene: Gnai1 Location: Chr5:18470133-18565353 bp, - strand Genetic Position: Chr5, 8.16 cM
• Alliance: Gnai1^tm1Lbi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:68071
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neo cassette was inserted into exon 3. (J:68071)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gnai1 Mutation: 15 strains or lines available

References

• Original: J:68071 Jiang M, et al., Most central nervous system D2 dopamine receptors are coupled to their effectors by Go. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3577-82
• All: 10 reference(s)