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Targeted Allele Detail
Symbol: Frzbtm1Nat
Name: frizzled-related protein; targeted mutation 1, Jeremy Nathans
MGI ID: MGI:3803336
Synonyms: sFRP3 KO
Gene: Frzb  Location: Chr2:80242314-80277740 bp, - strand  Genetic Position: Chr2, 48.13 cM
Germline Transmission:  Earliest citation of germline transmission: J:137890
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe first coding exon of the gene, coding for the cysteine rich domain, was replaced with the bacterial beta-Gal reporter gene and the PGKneo selectable marker, both in the plus orientation. (J:137890)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Frzb Mutation:  19 strains or lines available
Original:  J:137890 Nathans J, Generation of an Frzb mutant allele. MGI Direct Data Submission. 2008;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory