Robo4^tm1Aird
Targeted Allele Detail

Summary

• Symbol: Robo4^tm1Aird
• Name: roundabout guidance receptor 4; targeted mutation 1, William C Aird
• MGI ID: MGI:3803283
• Gene: Robo4 Location: Chr9:37313198-37325319 bp, + strand Genetic Position: Chr9, 20.76 cM
• Alliance: Robo4^tm1Aird page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137809
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exons 2 through 3 were replaced with a lacZ and neo cassette. (J:137809)

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Robo4 Mutation: 87 strains or lines available

References

• Original: J:137809 Okada Y, et al., A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium. Circ Res. 2007 Jun 22;100(12):1712-22
• All: 2 reference(s)