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Prom1tm1Rafi
Targeted Allele Detail
Summary
Symbol: Prom1tm1Rafi
Name: prominin 1; targeted mutation 1, Shahin Rafii
MGI ID: MGI:3802793
Synonyms: CD133lacZ, Prom1lacZ
Gene: Prom1  Location: Chr5:44150962-44259374 bp, - strand  Genetic Position: Chr5, 23.97 cM
Alliance: Prom1tm1Rafi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137714
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    Using the VelociGene technique, the lacZ gene was knocked into the gene replacing exons 3 through 8. (J:137714)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prom1 Mutation:  75 strains or lines available
References
Original:  J:137714 Shmelkov SV, et al., CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. J Clin Invest. 2008 Jun;118(6):2111-20
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory