Gata4^tm2.1Wtp
Targeted Allele Detail

Summary

• Symbol: Gata4^tm2.1Wtp
• Name: GATA binding protein 4; targeted mutation 2.1, William T Pu
• MGI ID: MGI:3801684
• Synonyms: Gata4^ap
• Gene: Gata4 Location: Chr14:63436371-63509141 bp, - strand Genetic Position: Chr14, 33.24 cM
• Alliance: Gata4^tm2.1Wtp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137426
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: Germ line, cre-mediated recombination removed the Gata4 cDNA and transcription STOP sequence leading to expression of the alkaline phosphatase gene. (J:137426)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata4 Mutation: 36 strains or lines available

References

• Original: J:137426 Zhou B, et al., Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature. 2008 Jul 3;454(7200):109-13
• All: 1 reference(s)