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Ranbp2tm1.1Jvd
Targeted Allele Detail
Nomenclature
Symbol: Ranbp2tm1.1Jvd
Name: RAN binding protein 2; targeted mutation 1.1, Jan M A van Deursen
MGI ID: MGI:3800899
Gene: Ranbp2  Location: Chr10:58446852-58494155 bp, + strand  Genetic Position: Chr10, 29.34 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137482
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsGerm line, cre-mediated recombination was used to remove exon 3. Lack of protein expression from this allele was confirmed by western blot analysis on heterozygous mouse embryonic fibroblast extracts. (J:137482)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ranbp2 Mutation:  50 strains or lines available
References
Original:  J:137482 Dawlaty MM, et al., Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha. Cell. 2008 Apr 4;133(1):103-15
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory