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Targeted Allele Detail
Symbol: Apoftm1(KOMP)Vlcg
Name: apolipoprotein F; targeted mutation 1, Velocigene
MGI ID: MGI:3800154
Synonyms: Apoftm1Vlcg
Gene: Apof  Location: Chr10:128268671-128270153 bp, + strand  Genetic Position: Chr10, 76.5 cM
Mutant Cell Lines:  10417A-D6, 10417A-H2, 10417B-H8
Germline Transmission:  Earliest citation of germline transmission: J:185314
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1296bp between positions 127705793-127707088 of Chromosome 10 (Genome Build37). The cassette inserted into exon 1. RT-PCR confirmed the absence of transcript expression in the liver. (J:136110)
Generation of the Apoftm1(KOMP)Vlcg allele
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 2 lines available
Carrying any Apof Mutation:  4 strains or lines available
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory