Gabpb1^tm1Hhx
Targeted Allele Detail

Summary

• Symbol: Gabpb1^tm1Hhx
• Name: GA repeat binding protein, beta 1; targeted mutation 1, Hai-Hui Xue
• MGI ID: MGI:3799311
• Synonyms: GABPbeta1L^-
• Gene: Gabpb1 Location: Chr2:126469362-126518257 bp, - strand Genetic Position: Chr2, 61.76 cM
• Alliance: Gabpb1^tm1Hhx page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137300
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 9 was replaced with a neo cassette. The absence of the long form protein product was confirmed by western blot analysis on thymocyte and splenocyte extracts. Expression of the short form protein is increased. (J:137300)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gabpb1 Mutation: 44 strains or lines available

References

• Original: J:137300 Xue HH, et al., Targeting the GA binding protein beta1L isoform does not perturb lymphocyte development and function. Mol Cell Biol. 2008 Jul;28(13):4300-9
• All: 1 reference(s)