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Mavstm1Tsc
Targeted Allele Detail
Nomenclature
Symbol: Mavstm1Tsc
Name: mitochondrial antiviral signaling protein; targeted mutation 1, Jurg Tschopp
MGI ID: MGI:3799298
Synonyms: Cardif-
Gene: Mavs  Location: Chr2:131234063-131248025 bp, + strand  Genetic Position: Chr2, 63.3 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136289
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 2, containing the initiation methionine, through exon 5 were replaced with a neo cassette. (J:136289)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mavs Mutation:  21 strains or lines available
References
Original:  J:136289 Michallet MC, et al., TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity. 2008 May;28(5):651-61
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory