About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Targeted Allele Detail
Symbol: Adcy1tm1.1Ito
Name: adenylate cyclase 1; targeted mutation 1.1, Shigeyoshi Itohara
MGI ID: MGI:3798842
Synonyms: AC1delta
Gene: Adcy1  Location: Chr11:7063489-7178506 bp, + strand  Genetic Position: Chr11, 4.72 cM, cytoband A2
Germline Transmission:  Earliest citation of germline transmission: J:137123
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsGerm line, cre-mediated recombination was used to remove exon 1. The absence of transcript expression was confirmed by RT-PCR on brain extracts. (J:137123)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy1 Mutation:  5 strains or lines available
Original:  J:137123 Iwasato T, et al., Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development. J Neurosci. 2008 Jun 4;28(23):5931-43
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 5.21
The Jackson Laboratory