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Adcy1tm1Ito
Targeted Allele Detail
Nomenclature
Symbol: Adcy1tm1Ito
Name: adenylate cyclase 1; targeted mutation 1, Shigeyoshi Itohara
MGI ID: MGI:3798841
Synonyms: AC1flox
Gene: Adcy1  Location: Chr11:7063489-7178506 bp, + strand  Genetic Position: Chr11, 4.72 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137123
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 1 was floxed and an frt-flanked neo cassette used for selection was removed by flp-mediated recombination. (J:137123)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy1 Mutation:  7 strains or lines available
References
Original:  J:137123 Iwasato T, et al., Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development. J Neurosci. 2008 Jun 4;28(23):5931-43
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory