Ptdss1^tm1Jev
Targeted Allele Detail

Summary

• Symbol: Ptdss1^tm1Jev
• Name: phosphatidylserine synthase 1; targeted mutation 1, Jean Vance
• MGI ID: MGI:3798813
• Synonyms: Pss1^-
• Gene: Ptdss1 Location: Chr13:67080894-67146465 bp, + strand Genetic Position: Chr13, 34.54 cM, cytoband B-C1
• Alliance: Ptdss1^tm1Jev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137106
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 and 4 were replaced with a neo cassette. The absence of transcript expression was confirmed by real time qPCR on brain, liver and heart extracts. (J:137106)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptdss1 Mutation: 38 strains or lines available

References

• Original: J:137106 Arikketh D, et al., Defining the importance of phosphatidylserine synthase-1 (PSS1): unexpected viability of PSS1-deficient mice. J Biol Chem. 2008 May 9;283(19):12888-97
• All: 1 reference(s)