Opn4tm1(cre)Sapa
Targeted Allele Detail
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Symbol: |
Opn4tm1(cre)Sapa |
Name: |
opsin 4 (melanopsin); targeted mutation 1, Satchidananda Panda |
MGI ID: |
MGI:3798479 |
Synonyms: |
mOpn4-Cre1D4, Opn4Cre |
Gene: |
Opn4 Location: Chr14:34312575-34322099 bp, - strand Genetic Position: Chr14, 20.83 cM, cytoband B
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Alliance: |
Opn4tm1(cre)Sapa page
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Germline Transmission: |
Earliest citation of germline transmission:
J:137151
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S
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Allele Type: |
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Targeted (Recombinase) |
Mutations: |
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Insertion, Intragenic deletion
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Opn4tm1(cre)Sapa expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The first 7 exons were replaced with a cassette containing a cre gene, IRES/betaTau, a floxed neo and eYFP gene. No YFP expression was detected in the retina. Cre activity is detected in the retinal ganglion cell layer.
(J:137151)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Opn4
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Opn4 Mutation: |
33 strains or lines available
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Original: |
J:137151 Hatori M, et al., Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses. PLoS One. 2008;3(6):e2451 |
All: |
9 reference(s) |
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