Tg(UBC-CYP19A1)21Mpo
Transgene Detail

Summary

• Symbol: Tg(UBC-CYP19A1)21Mpo
• Name: transgene insertion 21, Matti Poutanen
• MGI ID: MGI:3798062
• Synonyms: AROM+
• Transgene: Tg(UBC-CYP19A1)21Mpo Location: unknown
• Alliance: Tg(UBC-CYP19A1)21Mpo page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(UBC-CYP19A1)21Mpo expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CYP19A1 (1588)

  Cyp19a1

  (MGI:88587)

• Mutation details: A 1.0-kb-long ubiquitin C promoter drives the expression of a full-length human P450 aromatase cDNA. RT-PCR analysis showed that the transgene was expressed in the testis, and at a lower level in the heart, brain, and liver. In addition to line 21, line 33 was also generated. (J:70203)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:70203 Li X, et al., Altered structure and function of reproductive organs in transgenic male mice overexpressing human aromatase. Endocrinology. 2001 Jun;142(6):2435-42
• All: 14 reference(s)