Sosttm1(KOMP)Vlcg
Targeted Allele Detail
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Symbol: |
Sosttm1(KOMP)Vlcg |
Name: |
sclerostin; targeted mutation 1, Velocigene |
MGI ID: |
MGI:3797839 |
Synonyms: |
SostLacZ, SostLacZ-neo, Sosttm1Vlcg |
Gene: |
Sost Location: Chr11:101853284-101857841 bp, - strand Genetic Position: Chr11, 65.48 cM, cytoband D
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Alliance: |
Sosttm1(KOMP)Vlcg page
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IMPC: |
Sost gene page |
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Higher bone mass in Rr20tm1.1Vlcg/Rr20tm1.1Vlcg and Sosttm1(KOMP)Vlcg/Sosttm1(KOMP)Vlcg mice
Show the 1 phenotype image(s) involving this allele.
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Mutant Cell Lines: |
10069A-G10, 10069B-C7, 10069B-C10, 10069B-E8 |
Germline Transmission: |
Earliest citation of germline transmission:
J:167585
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Parent Cell Line: |
VGB6 (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Project Collection: |
KOMP-Regeneron
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: ZEN-Ub1
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Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3174bp between positions 101854623-101857796 of Chromosome 11 (Build GRCm39).
(J:136110, J:167585)
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View phenotypes and curated references for all genotypes (concatenated display).
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Cell line 10069B-C10 was successfully used to make chimeric mice. Germline transmission was accomplished. J:188586
Cell line 10069A-G10 was successfully used to make chimeric mice. Germline transmission was accomplished. J:167585
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Original: |
J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008; |
All: |
19 reference(s) |
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