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Transgene Detail
Symbol: Tg(CAG-EGFP,-ALPP)2.6Ggc
Name: transgene insertion 2.6, Giacomo Consalez
MGI ID: MGI:3797263
Synonyms: eGFP-F-IRES-hPLAP, piGAP
Transgene: Tg(CAG-EGFP,-ALPP)2.6Ggc  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Conditional ready, Reporter)
Mutation:    Insertion
Mutation detailsThe transgene was designed with a CMV enhancer/chicken beta-actin promoter (from pCAGGS vector) and loxP-flanked STOP-polyA sequence upstream of a farnesylated Enhanced Green Fluorescent Protein coding sequence (eGFP-F; from pEGFP-F plasmid (Clontech), eGFP fused to the carboxyl-terminal 20 amino acids of the human c-Ha-Ras protein, which targets GFP to the cytoplasmic side of the plasma membrane), internal ribosomal entry site (IRES), human Placental Alkaline Phosphatase cDNA sequence (PLAP or ALPP; from the pGTO plasmid), and SV40 polyA signal. (J:136874)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Original:  J:136874 Badaloni A, et al., Transgenic mice expressing a dual, CRE-inducible reporter for the analysis of axon guidance and synaptogenesis. Genesis. 2007 Jun;45(6):405-12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
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