Tg(KRT5-TVA)1Sao
Transgene Detail

Summary

• Symbol: Tg(KRT5-TVA)1Sao
• Name: transgene insertion 1, Sandra Orsulic
• MGI ID: MGI:3797115
• Synonyms: keratin 5-TVA
• Transgene: Tg(KRT5-TVA)1Sao Location: unknown
• Alliance: Tg(KRT5-TVA)1Sao page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The construct contains a 5.2 kb fragment of the bovine keratin 5 (KRT5) promoter controlling the avian retroviral receptor TVA cDNA (pg800 tva). A 0.6 kb fragment of the rabbit beta-globin intron and a 3'poly A sequence are also in the construct. Expression of the transgene is restricted to the ovarian surface epithelium. (J:75724)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:75724 Orsulic S, et al., Induction of ovarian cancer by defined multiple genetic changes in a mouse model system. Cancer Cell. 2002 Feb;1(1):53-62
• All: 2 reference(s)