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Synctm1Chen
Targeted Allele Detail
Nomenclature
Symbol: Synctm1Chen
Name: syncoilin; targeted mutation 1, Ju CHen
MGI ID: MGI:3797113
Gene: Sync  Location: Chr4:129287617-129308559 bp, + strand  Genetic Position: Chr4, 63.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136645
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neo cassette was inserted immediately after exon 2 altering the splice site. The absence of protein product was confirmed by western blot analysis. (J:136645)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sync Mutation:  11 strains or lines available
References
Original:  J:136645 Zhang J, et al., Syncoilin is required for generating maximum isometric stress in skeletal muscle but dispensable for muscle cytoarchitecture. Am J Physiol Cell Physiol. 2008 May;294(5):C1175-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory