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Mapttm3(cre/PGR)Aha
Targeted Allele Detail
Summary
Symbol: Mapttm3(cre/PGR)Aha
Name: microtubule-associated protein tau; targeted mutation 3, Akihiro Harada
MGI ID: MGI:3797111
Synonyms: tauCrePR
Gene: Mapt  Location: Chr11:104122216-104222916 bp, + strand  Genetic Position: Chr11, 67.79 cM, cytoband E1
Alliance: Mapttm3(cre/PGR)Aha page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136624
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    mifepristone
Mutation:    Insertion
 
Mapttm3(cre/PGR)Aha expression driven by 1 gene
 
Mutation detailsAn inducible cre/PGR (progesterone receptor) fusion gene followed by a neo cassette was inserted upstream of exon 1. Cre expression is neuron specific. (J:136624)
Recombinase
activity
Activity:
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Driver: Mapt (mouse)
Summary of all recombinase alleles driven by Mapt.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapt Mutation:  428 strains or lines available
References
Original:  J:136624 Hashimoto Y, et al., Neuron-specific and inducible recombination by Cre recombinase in the mouse. Neuroreport. 2008 Apr 16;19(6):621-4
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory