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Targeted Allele Detail
Symbol: Mecp2tm1Csb
Name: methyl CpG binding protein 2; targeted mutation 1, Cecile Spielewoy Blaustein
MGI ID: MGI:3797096
Synonyms: MeCP2-EGFP
Gene: Mecp2  Location: ChrX:74026592-74085690 bp, - strand  Genetic Position: ChrX, 37.63 cM
Germline Transmission:  Earliest citation of germline transmission: J:136605
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA cassette containing an EGFP, a STOP codon and a floxed neo was inserted at the STOP translation codon to create a fusion gene. Germ line, cre-mediated recombnation was used to remove the neo cassette. (J:136605)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mecp2 Mutation:  29 strains or lines available
Original:  J:136605 Schmid RS, et al., A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome. Neuroreport. 2008 Mar 5;19(4):393-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory