Ch25h^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Ch25h^{tm1(KOMP)Vlcg}
• Name: cholesterol 25-hydroxylase; targeted mutation 1, Velocigene
• MGI ID: MGI:3797009
• Synonyms: Ch25h^tm1Vlcg
• Gene: Ch25h Location: Chr19:34451183-34452548 bp, - strand Genetic Position: Chr19, 29.69 cM
• Alliance: Ch25h^{tm1(KOMP)Vlcg} page
• IMPC: Ch25h gene page

Mutation origin

• Mutant Cell Lines: 10020A-A4, 10020A-A7, 10020A-A9, 10020A-A11, 10020A-B2, 10020A-B5, 10020K-A5
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 970bp between positions 34451554-34452523 of Chromosome 19 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Ch25h Mutation: 20 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)