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Ibsptm1Jeau
Targeted Allele Detail
Nomenclature
Symbol: Ibsptm1Jeau
Name: integrin binding sialoprotein; targeted mutation 1, Jane E Aubin
MGI ID: MGI:3796255
Synonyms: BSP-
Gene: Ibsp  Location: Chr5:104299171-104311469 bp, + strand  Genetic Position: Chr5, 50.68 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136223
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on femur extracts. (J:136223)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ibsp Mutation:  15 strains or lines available
References
Original:  J:136223 Malaval L, et al., Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis. J Exp Med. 2008 May 12;205(5):1145-53
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory