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Targeted Allele Detail
Symbol: Aicdatm2Mnz
Name: activation-induced cytidine deaminase; targeted mutation 2, Michel C Nussenzweig
MGI ID: MGI:3796170
Synonyms: Aicda155
Gene: Aicda  Location: Chr6:122553809-122564180 bp, + strand  Genetic Position: Chr6, 57.65 cM, cytoband F2
Germline Transmission:  Earliest citation of germline transmission: J:136224
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J/J
Allele Type:    Targeted
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe Mirn155 seed sequence was removed from the 3'UTR and a self-excising neo cassette downstream of exon 4. The final allele does not contain the neo cassette. (J:136224)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aicda Mutation:  47 strains or lines available
Original:  J:136224 Dorsett Y, et al., MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation. Immunity. 2008 May;28(5):630-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory