About   Help   FAQ
Aicdatm2Mnz
Targeted Allele Detail
Nomenclature
Symbol: Aicdatm2Mnz
Name: activation-induced cytidine deaminase; targeted mutation 2, Michel C Nussenzweig
MGI ID: MGI:3796170
Synonyms: Aicda155
Gene: Aicda  Location: Chr6:122553809-122564180 bp, + strand  Genetic Position: Chr6, 57.65 cM, cytoband F2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136224
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J/J
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe Mirn155 seed sequence was removed from the 3'UTR and a self-excising neo cassette downstream of exon 4. The final allele does not contain the neo cassette. (J:136224)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aicda Mutation:  47 strains or lines available
References
Original:  J:136224 Dorsett Y, et al., MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation. Immunity. 2008 May;28(5):630-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/06/2021
MGI 6.16
The Jackson Laboratory