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Akirin1tm1.1Aki
Targeted Allele Detail
Nomenclature
Symbol: Akirin1tm1.1Aki
Name: akirin 1; targeted mutation 1.1, Shizuo Akira
MGI ID: MGI:3796164
Gene: Akirin1  Location: Chr4:123734559-123750345 bp, - strand  Genetic Position: Chr4, 57.42 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130487
Parent Cell Line:  GSI-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsGerm line, cre-mediated recombination was used to remove exon 1. The absence of transcript was confirmed in mouse embryonic fibroblasts by northern blot analysis. (J:130487)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akirin1 Mutation:  7 strains or lines available
References
Original:  J:130487 Goto A, et al., Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. Nat Immunol. 2008 Jan;9(1):97-104
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory