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Targeted Allele Detail
Symbol: Bdkrb1tm1(BDKRB1)Jfh
Name: bradykinin receptor, beta 1; targeted mutation 1, J Fred Hess
MGI ID: MGI:3795262
Gene: Bdkrb1  Location: Chr12:105604091-105605511 bp, + strand  Genetic Position: Chr12, 55.81 cM, cytoband F1
Germline Transmission:  Earliest citation of germline transmission: J:135789
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutation:    Insertion
Bdkrb1tm1(BDKRB1)Jfh expresses 1 gene
Mutation detailsThe mouse open reading frame was replaced with the human one and a floxed neo cassette. Germ line, cre-mediated recombination was used to remove the neo cassette. This is a null allele and a knock in allele. (J:135789)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bdkrb1 Mutation:  12 strains or lines available
Original:  J:135789 Hess JF, et al., Generation and characterization of a humanized bradykinin B1 receptor mouse. Biol Chem. 2006 Feb;387(2):195-201
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
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