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Nrastm1Mok
Targeted Allele Detail
Nomenclature
Symbol: Nrastm1Mok
Name: neuroblastoma ras oncogene; targeted mutation 1, Moyota Katsuki
MGI ID: MGI:3794957
Synonyms: N-ras-
Gene: Nras  Location: Chr3:103058285-103067914 bp, + strand  Genetic Position: Chr3, 45.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:135610
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 and 2 were replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on E11.5 embryo extracts. (J:135610)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 7 strains available      Cell Lines: 0 lines available
Carrying any Nras Mutation:  30 strains or lines available
References
Original:  J:135610 Nakamura K, et al., Partial functional overlap of the three ras genes in mouse embryonic development. Oncogene. 2008 May 8;27(21):2961-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/17/2017
MGI 6.10
The Jackson Laboratory