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Wt1tm1Mlh
Targeted Allele Detail
Nomenclature
Symbol: Wt1tm1Mlh
Name: Wilms tumor 1 homolog; targeted mutation 1, Martin L Hooper
MGI ID: MGI:3794650
Synonyms: Wt1tmT396
Gene: Wt1  Location: Chr2:105126529-105173616 bp, + strand  Genetic Position: Chr2, 55.06 cM, cytoband E
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:135449
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wt1 Mutation:  8 strains or lines available
References
Original:  J:135449 Patek CE, et al., Effects on kidney disease, fertility and development in mice inheriting a protein-truncating Denys-Drash syndrome allele (Wt1 (tmT396)). Transgenic Res. 2008 Jun;17(3):459-75
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory