About   Help   FAQ
Targeted Allele Detail
Symbol: Abcc5tm1Bor
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 5; targeted mutation 1, Piet Borst
MGI ID: MGI:3794119
Gene: Abcc5  Location: Chr16:20331303-20426394 bp, - strand  Genetic Position: Chr16, 12.41 cM
Germline Transmission:  Earliest citation of germline transmission: J:135561
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 1.5 kb segment of genomic DNA containing exon 17 that encodes amino acids 678 to 745 of the first ATP-binding domain was replaced with a hygro cassette. The absence of protein product was confirmed by western blot analysis on erythrocye vesicle extracts. (J:135561)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abcc5 Mutation:  71 strains or lines available
Original:  J:135561 de Wolf CJ, et al., cGMP transport by vesicles from human and mouse erythrocytes. FEBS J. 2007 Jan;274(2):439-50
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory