About   Help   FAQ
Tg(H2-Ab1)62Dim
Transgene Detail
Nomenclature
Symbol: Tg(H2-Ab1)62Dim
Name: transgene insertion 62, Diane Mathis
MGI ID: MGI:3793693
Synonyms: Ab62
Transgene: Tg(H2-Ab1)62Dim  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(H2-Ab1)62Dim expresses 1 gene
 
Mutation detailsA transgenic construct containing the entire mouse (AKR/J strain) H2-Ab1 kappa genomic DNA sequence was microinjected into (C57BL/6 x SJL)F2 embryos, generating line Aalpha62. Line 62 was crossed to mice carrying Tg(H2-Aa)26Dim and the resulting double transgenic line was donated to The Jackson Laboratory. The construct was also injected into C57BL/6 embryos to have the transgene on a homogeneous genetic background. Line 42 was established (Aalpha42). S1-mapping shows normal patterns of high expression in spleen, lung and thymus. (J:110897)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:110897 Fehling HJ, et al., Functional consequences of overexpressed Ia antigens in AK alpha/AK beta transgenic mice. J Immunol. 1990 Apr 15;144(8):2865-74
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory