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Transgenic Allele Detail
Symbol: Lactb2Tg(Igh-Meis1)2770Amb
Name: lactamase, beta 2; transgene insertion 2770, Arthur M Buchberg
MGI ID: MGI:3793472
Synonyms: Tg2770
Gene: Lactb2  Location: Chr1:13696117-13731424 bp, - strand  Genetic Position: Chr1, 4.29 cM
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutations:    Insertion, Intragenic deletion
Lactb2Tg(Igh-Meis1)2770Amb expresses 1 gene
Mutation detailsA transgene was constructed in which the Igh promoter and enhancers were used to drive expression of the Meis1 cDNA (transcript a). Sequencing of line 2770 revealed the integration site to be located within Lactb replacing a 21.3 kb segment containing exons 5 through 7. (J:79618)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lactb2 Mutation:  19 strains or lines available
Original:  J:79618 Sollars VE, et al., A novel transgenic line of mice exhibiting autosomal recessive male-specific lethality and non-alcoholic fatty liver disease. Hum Mol Genet. 2002 Nov 1;11(22):2777-86
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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