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Mirc3tm1.1Tyj
Targeted Allele Detail
Nomenclature
Symbol: Mirc3tm1.1Tyj
Name: microRNA cluster 3, including Mir25 through Mir106b; targeted mutation 1.1, Tyler Jacks
MGI ID: MGI:3790969
Synonyms: miR-106b~25delta
Gene: Mirc3  Location: Chr5:138163583-138164080 bp  Genetic Position: Chr5, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134861
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intergenic deletion
 
Mutation detailsThe Frt-flanked neomycin cassette replacing the microRNA cluster was removed through Flp-mediated excision. (J:134861)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 155937 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mirc3 Mutation:  1 strain or line available
References
Original:  J:134861 Ventura A, et al., Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 2008 Mar 7;132(5):875-86
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory