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Dpysl4tm1Ttq
Targeted Allele Detail
Nomenclature
Symbol: Dpysl4tm1Ttq
Name: dihydropyrimidinase-like 4; targeted mutation 1, Tam T Quach
MGI ID: MGI:3790672
Synonyms: CRMP3-
Gene: Dpysl4  Location: Chr7:139085981-139101795 bp, + strand  Genetic Position: Chr7, 83.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134800
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 3 was replaced with an IRES-lacZ-neo cassette. The absence of protein product was confirmed by western blot analysis on hippocampus extracts. This is a null allele and a reporter allele. (J:134800)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dpysl4 Mutation:  2 strains or lines available
References
Original:  J:134800 Quach TT, et al., CRMP3 is required for hippocampal CA1 dendritic organization and plasticity. FASEB J. 2008 Feb;22(2):401-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory