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Tlx3tm1(cre)Qima
Targeted Allele Detail
Nomenclature
Symbol: Tlx3tm1(cre)Qima
Name: T cell leukemia, homeobox 3; targeted mutation 1, Qiufu Ma
MGI ID: MGI:3789185
Synonyms: Rnx-Cre, Tlx3Cre
Gene: Tlx3  Location: Chr11:33200752-33203588 bp, - strand  Genetic Position: Chr11, 19.21 cM, cytoband A5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134327
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsA cre cassette followed by an frt-flanked neo was inserted into exon 2. Germ-line, flp-mediated recombination was used to remove the neo cassette. Cre expression recapitulates endogenous promoter activity. (J:134327)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tlx3     Summary of all recombinase alleles driven by Tlx3. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tlx3 Mutation:  9 strains or lines available
References
Original:  J:134327 Xu Y, et al., Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons. J Neurosci. 2008 Apr 9;28(15):4037-46
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory