Slc45a2^uw-4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Slc45a2^uw-4Btlr
• Name: solute carrier family 45, member 2; underwhite 4 Bruce Beutler
• MGI ID: MGI:3784986
• Synonyms: Slc45a2^m4Btlr, sweater
• Gene: Slc45a2 Location: Chr15:11000807-11029319 bp, + strand Genetic Position: Chr15, 5.4 cM
• Alliance: Slc45a2^uw-4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation corresponds to an A-to-C transversion at nucleotide position 794 of the gene (Genbank: NM_053077), in the third of 7 exons, resulting in replacement of histidine at amino acid postion 233 by proline (H233P) in the sixth transmembrane domain of the protein. (J:133631)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc45a2 Mutation: 55 strains or lines available

References

• Original: J:133631 Blasius A, et al., Sweater is an allele of Slc45a2 and displays pigmentation defects. MGI Direct Data Submission. 2008
• All: 1 reference(s)