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Tg(Rag2-EGFP)1Mnz
Transgene Detail
Nomenclature
Symbol: Tg(Rag2-EGFP)1Mnz
Name: transgene insertion 1, Michel C Nussenzweig
MGI ID: MGI:3784416
Synonyms: NG-BAC, RAG2/GFP, Rag2pGFP, RAG2p-GFP
Transgene: Tg(Rag2-EGFP)1Mnz  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA mouse BAC clone Containing Rag1 and Rag2 was obtained from Research Genetics. An EGFP cDNA was inserted in this clone at the start codon of Rag2 by homologous recombination. A termination codon is present at the end of the EGFP sequence. 3 lines were generated and found to have identical GFP expression. This is a representative transgene for all 3 lines. (J:56779)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:56779 Yu W, et al., Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization [see comments]. Nature. 1999 Aug 12;400(6745):682-7
All:  49 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory