Tpp2tm1Gnie
Targeted Allele Detail
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Symbol: |
Tpp2tm1Gnie |
Name: |
tripeptidyl peptidase II; targeted mutation 1, Gabriele Niedermann |
MGI ID: |
MGI:3783749 |
Gene: |
Tpp2 Location: Chr1:43973130-44042160 bp, + strand Genetic Position: Chr1, 23.5 cM
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Alliance: |
Tpp2tm1Gnie page
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Germline Transmission: |
Earliest citation of germline transmission:
J:133572
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Parent Cell Line: |
W4 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted downstream of exon 12 and an additional loxP site was inserted upstream of exon 11. Germ-line, flp-mediated recombination was used to remove the neo cassette leaving exons 11 and 12 floxed.
(J:133572)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tpp2 Mutation: |
80 strains or lines available
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Original: |
J:133572 Huai J, et al., Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice. Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5177-82 |
All: |
1 reference(s) |
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