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Rcan1tm1Emar
Targeted Allele Detail
Nomenclature
Symbol: Rcan1tm1Emar
Name: regulator of calcineurin 1; targeted mutation 1, Eulalia Marti
MGI ID: MGI:3783735
Gene: Rcan1  Location: Chr16:92391953-92466146 bp, - strand  Genetic Position: Chr16, 53.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132745
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 6 through part of exon 7 was replaced with a neo cassette. The absence of protein was confirmed by western blot analysis on cultured primary neuron extracts. (J:132745)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rcan1 Mutation:  16 strains or lines available
References
Original:  J:132745 Porta S, et al., RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration. Hum Mol Genet. 2007 May 1;16(9):1039-50
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory