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Cdh13tm1Brns
Targeted Allele Detail
Nomenclature
Symbol: Cdh13tm1Brns
Name: cadherin 13; targeted mutation 1, Barbara Ranscht
MGI ID: MGI:3778287
Synonyms: T-cadherin-, Tcad KO
Gene: Cdh13  Location: Chr8:118283733-119324921 bp, + strand  Genetic Position: Chr8, 65.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132759
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neo cassette was inserted into exon 5 that encodes the extracellular domain. The absence of protein product was confirmed by western blot analysis on fat pad extracts. (J:132759)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh13 Mutation:  3 strains or lines available
References
Original:  J:132759 Hebbard LW, et al., T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model. Cancer Res. 2008 Mar 1;68(5):1407-16
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/17/2015
MGI 5.21
The Jackson Laboratory