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Pnpg
Chemically induced Allele Detail
Nomenclature
Symbol: Pnpg
Name: purine-nucleoside phosphorylase; NP-1G
MGI ID: MGI:3777975
Synonyms: Np-1g
Gene: Pnp  Location: Chr14:51181760-51190869 bp, + strand  Genetic Position: Chr14, 26.31 cM, cytoband B-C1
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis allele was identified in the progeny of a cross between ENU mutagenized C57BL/6J males and C3H/HeHa females. A T to C transition occurred at nucleotide 46 resulting in a W16R amino acid change in the resulting protein. (J:522, J:39328)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pnp Mutation:  19 strains or lines available
References
Original:  J:522 Snyder FF, Genetic models of purine nucleoside phosphorylase deficiency in the mouse. Adv Exp Med Biol. 1991;309B:137-40
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/07/2021
MGI 6.17
The Jackson Laboratory