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Rettm2.1Heno
Targeted Allele Detail
Nomenclature
Symbol: Rettm2.1Heno
Name: ret proto-oncogene; targeted mutation 2.1, Hideki Enomoto
MGI ID: MGI:3777556
Synonyms: RetCFP
Gene: Ret  Location: Chr6:118151745-118197718 bp, - strand  Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132854
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsGerm-line, cre-mediated recombination was used to remove the human RET cassette leaving the CFP cassette intact. This is also a null allele. (J:132854)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ret Mutation:  35 strains or lines available
References
Original:  J:132854 Gould TW, et al., The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes. J Neurosci. 2008 Feb 27;28(9):2131-46
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory