Card6^tm1Aldu
Targeted Allele Detail

Summary

• Symbol: Card6^tm1Aldu
• Name: caspase recruitment domain family, member 6; targeted mutation 1, Almut Dufner
• MGI ID: MGI:3776907
• Gene: Card6 Location: Chr15:5125463-5138021 bp, - strand Genetic Position: Chr15, 1.99 cM
• Alliance: Card6^tm1Aldu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132634
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette with a 3' loxP site was inserted upstream of the fourth coding exon and an additional loxP site was inserted downstream of the coding region. (J:132634)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Card6 Mutation: 54 strains or lines available

References

• Original: J:132634 Dufner A, et al., CARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation. Mol Cell Biol. 2008 Mar;28(5):1541-52
• All: 1 reference(s)