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Tg(CD34-tTA,-CD34)1Dgt
Transgene Detail
Nomenclature
Symbol: Tg(CD34-tTA,-CD34)1Dgt
Name: transgene insertion 1, Daniel G Tenen
MGI ID: MGI:3776898
Synonyms: CD34tTA
Transgene: Tg(CD34-tTA,-CD34)1Dgt  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Transactivator)
Mutation:    Insertion
 
Tg(CD34-tTA,-CD34)1Dgt expresses 1 gene
 
Mutation details110 kb of human CD34 promoter sequence was placed upstream of a tTA tetracycline transactivator gene followed by an IRES domain and the coding genomic sequence for human CD34. Expression of both genes was detected in numerous tissues including heart and bone marrow. (J:132476)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:132476 Radomska HS, et al., Transgenic targeting with regulatory elements of the human CD34 gene. Blood. 2002 Dec 15;100(13):4410-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory