Tg(CD34-tTA,-CD34)1Dgt
Transgene Detail

Summary

• Symbol: Tg(CD34-tTA,-CD34)1Dgt
• Name: transgene insertion 1, Daniel G Tenen
• MGI ID: MGI:3776898
• Synonyms: CD34tTA
• Transgene: Tg(CD34-tTA,-CD34)1Dgt Location: unknown
• Alliance: Tg(CD34-tTA,-CD34)1Dgt page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Transactivator)
• Mutation: Insertion
• Tg(CD34-tTA,-CD34)1Dgt expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD34 (947)

  Cd34	(MGI:88329)

• Mutation details: 110 kb of human CD34 promoter sequence was placed upstream of a tTA tetracycline transactivator gene followed by an IRES domain and the coding genomic sequence for human CD34. Expression of both genes was detected in numerous tissues including heart and bone marrow. (J:132476)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:132476 Radomska HS, et al., Transgenic targeting with regulatory elements of the human CD34 gene. Blood. 2002 Dec 15;100(13):4410-9
• All: 2 reference(s)